Houston is coming off a convincing 30-10 season-opening win at home over the Miami Dolphins. Running back Arian Foster rushed for 79 yards and scored two touchdowns, while receiver Andre Johnson kicked the 2012 campaign off in a big way, catching eight passes for 119 yards and a touchdown.
The Jaguars, on the other hand, return home after an overtime loss in Minnesota to the Vikings, 26-23. There were positives for Jacksonville to take away from the defeat, however, as quarterback Blaine Gabbert threw for 260 yards and two touchdowns and star running back Maurice Jones-Drew, after an extended offseason holdout, was the team's leading rusher with 77 yards on 19 carries.
Elsewhere in the AFC South, Andrew Luck and the Indianapolis Colts play their home-opener against the Vikings and the Tennessee Titans look to rebound following their home loss to the New England Patriots with a road contest out west against the San Diego Chargers.
For the complete NFL schedule for Week 2, head over here.