Houston won Tuesday's contest 5-3, after dropping Monday night's game 8-7 in extra innings.
Both Brad Mills and Bud Black have announced the starting lineups for Wednesday's game, and they are as follows:
San Diego Padres
Harrell will look to head over the .500 mark with his win/loss record, as he comes into the start with a 6-6 record, to go along with a 4.77 ERA and 1.35 WHIP. Harrell was a tough luck loser last week, as he allowed just one run on two hits over seven innings, but got hung with the loss.
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