The Houston Astros lost 12-4 on Saturday, doomed by a fifth inning meltdown that saw the Arizona Diamondbacks score nine runs.

The Astros would take a 3-1 lead into the inning, with starter Jordan Lyles doomed by by a wild pitch and several bases loaded hits by the Diamondbacks before being lifted for relief pitcher Xavier Cedeno. The damage was far from done, however, as Arizona would score four more times in the inning on a Jose Altuve error and an Aaron Hill home run.

Lyles would end the game allowing seven runs (five earned) in just four innings.

Tyler Greene was one of the few bright spots for Houston, going 2-for-4 in the game with two RBIs, with catcher Chris Snyder also driving in two runs in the game.

Houston has now lost the first two games in the series against Arizona and will hope to avoid the sweep tomorrow, with Armando Gallaraga taking the mound for the Astros at 2:05 p.m. CDT.

Read more on the Astros at The Crawfish Boxes and SB Nation Houston. Head over to AZ Snake Pit and SB Nation Arizona for more on the Diamondbacks. Baseball Nation is your source for news and analysis around Major League Baseball.