The Houston Astros lost the second game of a three-game series against San Francisco on Wednesday night, falling 6-4 to the Giants at Minute Maid Park in Houston. The loss gives the Astros (40-90) their 11th in the last 12 games.

The Giants (73-57) jumped out in front in the top of the first, posting a four-run inning with the help of a three-run home run by Hunter Pence.

Houston engineered three runs over the next two innings to cut into the lead. Catcher Chris Snyder scored after doubling in the second, while a four-hit third inning resulted in two more runs. But the Giants recovered the padded lead when Joaquin Arias drove home Pence and Pablo Sandoval on a sixth-inning triple.

Despite giving up less hits than his opposing starter, Dallas Keuchel (1-7) took the loss for the Astros due to the four-run first. Barry Zito lasted just 2-1/3 innings after giving up seven hits, with the win going to George Kontos (1-0).

The three-game series concludes tomorrow night as Astros pitcher Jordan Lyles (3-10, 5.47 ERA) faces Ryan Vogelsong (11-7, 2.90 ERA) for the Giants.

For more on the Astros check out The Crawfish Boxes and SB Nation Houston, for everything on the Giants visit McCovey Chronicles and SB Nation Bay Area.