The injury will hurt Tannehill's chances of solidifying himself as the No. 3 QB in the 2012 Draft.
The Senior Bowl, which will be held in Mobile, Alabama on Jan. 28, is one of the biggest events of the pre-draft season, with the nation's top prospects battling it out in week-long practices watched by scouts and decision-makers for all 32 NFL franchises.
The 6'4 222 senior took over the Texas A&M QB position midway through last season after beginning his career as a WR.
He showcased a strong arm and excellent athleticism as a senior, completing 61.6% of his passes for 3,744 yards, 29 TD's and 15 INT's while rushing for 306 yards and 4 TD's on 5.3 yards per carry.
However, his inability to pull the Aggies out of their late-season skid will be questioned by many teams, especially after a lackluster performance against arch-rival Texas in his last game at Kyle Field.
The injury will prevent him from trying to answer some of those questions at the Senior Bowl, although it is still unclear whether he'll be healthy enough to throw at the NFL combine or in other pre-draft workouts closer to April.