Flushing, NY (Sports Network) - Brett Myers tossed seven strong scoreless innings while Carlos Lee hit a two-run shot and drove in three runs as Houston downed the New York Mets, 4-1, in the middle test of three between the clubs at Citi Field.
Tommy Manzella finished 3-for-4 and knocked in the other run for the Astros, who lost the series opener but have taken six of their last seven.
Myers (10-7) reached double-digit wins for the sixth time in his career by scattering six hits and striking out six and issuing one walk. He also extended his franchise-best streak from the start of the season with his 27th outing of six-or-more innings.
Brandon Lyon recorded a scoreless ninth for his ninth save.
Ike Davis doubled among his two hits for the Mets, who have lost three of four.
Johan Santana (10-9) surrendered eight hits and four runs with four strikeouts over seven full frames in the setback. The veteran lefty has lost his last three decisions and also saw his streak of three straight complete games snapped.
Lee's RBI single in the first got Houston on the board, then later in the frame Manzella's infield single plated a second run.
Houston tacked on two more in the fifth as Santana plunked Michael Bourn to start the inning and he scored on a two-run shot by Lee.
Myers did not allow a runner past second base during his entire outing, and stranded pinch-hitter Mike Hessmanon first to end his performance by fanning Angel Pagan looking.
Wilton Lopez began the eighth and the Mets tallied as Luis Castillo reached on an infield hit, advanced on a groundout and scored on a David Wright single. Davis added a base hit and two batters later Tim Byrdak came in to retire Josh Thole on a liner.
Lyon had less trouble in the ninth, setting down the Mets in order.
Myers' career-best in wins was 14, coming in 2003 with the Phillies...He last hit the 10-win mark in 2008 with Philadelphia by going 10-13...Dwight Gooden had been the last Mets pitcher to throw four straight complete games, from April 18-May 1, 1988.