Several headliners will be playing their first match of the 2012 U.S. Open on Wednesday, Day 3, as second-round play of the tournament continues in Flushing Meadows, N.Y.
John Isner, the top-seeded American and No. 9 overall, will begin his opening-round following Victoria Azarenka's second-round match at 11 a.m. ET. Azarenka, the women's top seed, will face unseeded Kirsten Flipkens of Belgium.
Isner's match is scheduled to start no earlier than 1 p.m. ET and he will be taking on Belgian Xavier Malisse.
No. 23 and fan-favorite Kim Clijsters will make it three Belgians in a row on the main court when she meets Laura Robson of Great Britain for her second-round match. They will face off after Isner's match.
Both three-seeds Maria Sharapova and Andy Murray highlight the evening session at Arthur Ashe Stadium. This will be second-round matches for both of them. Sharapova is up first at 7 p.m. ET against Spaniard Lourdes Dominguez Lino. Murray follows against Ivan Dodig of Croatia.
For the full schedule of events and scores at the 2012 U.S. Open, go here. ESPN2 and ESPN3 will handle the television coverage.