The Astros will send Jordan Lyles (3-11, 5.55 ERA) to the mound on Tuesday evening. In his last start, he gave up five runs and seven hits to the Pittsburgh Pirates in 4 2/3 innings last Tuesday.
Justin Germano (2-6, 6.16 ERA) will start for the Cubs. He has lost his last four starts and he gave up seven runs (six earned) and seven hits in four innings last Thursday against the Washington Nationals.
First pitch is scheduled for 7:05 p.m. CT at Minute Maid Park. It can be seen on Fox Sports Houston.
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