For the first time in franchise history, Houston sent exactly 27 batters up, and all 27 went down. San Francisco Giants' pitcher Matt Cain threw a perfect game on Wednesday night, the first such feat at the expense of the Astros. Cain's perfect game was only the 22nd in MLB history, and only the fifth no-hitter thrown against Houston:
- The last time Houston was no-hit: 2008: against the Cubs and Carlos Zambrano in 2008, a game played in Milwaukee's Miller Park due to Hurricane Ike.
- The closest an Astros player came to getting on base? Cain went to a 3-2 pitch count four times.
- One minor bit of controversy is the would-be double Jordan Schafer thought he hit in the top of the fourth inning. The grounder dropped along the first base line and was called foul, despite protests from Schafer and manager Brad Mills.
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