Looking to take the rubber match and series against the St. Louis Cardinals, the Astros trail 3-2 after four innings.
Starter J.A. Happ has given up three earned runs on three hits over the four innings.
Houston took the first lead when Jed Lowrie hit a solo homer in the bottom of the first. The Astros extended the lead to 2-0 when Chris Johnson doubled home Brett Wallace.
But the Cardinals scored three in the following frame thanks to three hits and two walks. Houston is 1-7 in rubber matches this season, losing the last seven.