The Texans official Twitter feed is reporting that the Texans will be without starting right guard Mike Brisiel for a couple of weeks:
Mike Brisiel is going to miss a couple weeks. He has a sprained MCL. Hope is that he’ll return after bye. Antoine Caldwell will replace him.
Caldwell and Brisiel had been splitting time, although Brisiel had earned a larger share over the past couple of weeks. It could have happened at a worse position, so the Texans shouldn’t feel too bad.